Note, the pills do not work like Tarot cards which effects can be learned before use, the color of a pill does not foretell its effect in any way.

They come in many colors and the effects change every time you play. Rebirth was released for Microsoft Windows, OS X, Linux, PlayStation 4, and PlayStation Vita in November 2014, and for Xbox One, New Nintendo 3DS, and Wii U in July 2015. Pills are random items that are dropped by enemies, found in chests, or spawned in rooms. Rebirth brings back everything that the original game had and much much more, including 350+ new items, 10 playable characters, 100+ new enemies, over 50 bosses and tons of new secrets to find. The Binding of Isaac: Rebirth is an indie roguelike video game designed by Edmund McMillen and developed and published by Nicalis. Made in a completely new shiny C++ based engine, Rebirth overcomes a lot of the downfalls from the original game, which suffered as it took the Flash engine to its limits. It is a remake of the original Binding of Isaac and features several improvements to the gameplay mechanics, including expanded item roster and co-op multiplayer.

Much like the original, the game is a randomly developed action RPG with rogue-like elements, however with Rebirth the art (as well as the entire game) has been revamped and remake with a pixel art 16-bit style in mind. The Binding of Isaac: Rebirth is a roguelike game, developed and published by Nicalis. I think its left ctrl on keyboard for those wondering, not 100 sure. It was designed by Edmund McMillen and produced and developed by Nicalis for Steam, PS4 and Playstation Vita, with possibilities of future Nintendo and Xbox console ports. This also lets you drop cards/pills/runes so if you want to drop that wizard pill before you accidentally use it you can. The Binding of Isaac: Rebirth is the remake of the original Binding of Isaac game. The Binding of Isaac: Rebirth About The Binding of Isaac: Rebirth - Info

The binding of isaac rebirth items